I-API Raw Matter Lupinol Powder
1. Isingeniso se- Lupinol Powder:
ILupinol iyindawo yokuhlanganisa i-anvil ye-pentacyclic engakhishwa ezithelo nemifino ehlukahlukene njengama-sitrobheli kanye nama-mango, kanye nezitshalo ezinjengamakhambi ama-chinese. Inemiphumela emikhemeni efana nokulwa nokuvuvukala, i-antioxidant, futhi ikhuthaza ukusebenza ngamanxeba, futhi ikhombise umsebenzi wokulwa nomdlavuza emidlalweni ye-pancreatic, umdlavuza webele, nomdlavuza webele, kanye ne-melanoma, futhi isetshenziswa emtholampilo ekwelapheni i-leukemia, Umdlavuza wesibindi, umdlavuza wekoloni, umdlavuza we-pancreatic, nezinye izifo.
2. Imininingwane eyisisekelo :
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Product Name
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Lupinol
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Specification
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8%
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Appearance
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White to off-white powder
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CAS No.
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545-47-1
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Molecular formula
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C30H50O
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Molecular weight
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426.73
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EINECS No.
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208-889-9
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Melting point
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215°C
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Boiling point
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482.1 (rough estimate)
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3. Sebenza
1. Imiphumela ye-Anti-Status
(1) Umphumela wokuvimbela ku-melanoma
ILupinol inomthelela ovimbayo ekukhuleni nasekungenisweni kokwehlukanisa i-melanoma yegundane.
(2) Umphumela wokuvimbela umdlavuza wesikhumba kumagundane
ILupinol inomthelela ovimbayo ekuthuthukisweni komdlavuza wesikhumba kanye nokuvezwa kwezimpawu zalo ze-tumor.
(3) Umphumela wokuvimbela umdlavuza webele
ILupinol inomthelela ovimbayo ekukhuleni kwamangqamuzana omdlavuza webele.
(4) Inhibitory ne-apoptosis-inducting imiphumela evusa amaseli womdlavuza we-Prostate
Phakathi kwamathumbu ahlobene ne-endocrine, ngaphezu kwamaseli womdlavuza webele, uLupinol nawo unomphumela wokuvimbela umdlavuza we-Prostate.
(5) Inhibitory ne-apoptosis-efutha imiphumela yokufaka umdlavuza we-pancreatic
ILupinol inomphumela wokukhulisa inhibitory kumdlavuza we-pancreatic, nokuvinjwa kwe-RAS Payway kuncenga i-apoptosis kumaseli womdlavuza we-pancreatic.
(6) Umphumela wokuvimbela ku-Hepatocellular Carcinoma
ILupinol ivimbela amandla okuzivuselela amaseli ezinhlamnyetali (tic) e-vitro naseVivo.
(7) Umphumela wokuvimbela amaseli we-leukemia
ILupinol inokukhula kokukhulisa okuvinjelwe kanye ne-apoptosis-efuthani umphumela kumaseli we-leukemia. Umphumela wokuvinjwa kweLupinol kumaseli we-Leukemia uhlobene ne-carbonylation yendandatho ye-lupine.
(8) imiphumela yokuvimbela kwamanye ama-tumors
ILupinol inomphumela wokuvimbela emgodini nasentanjeni. ILupinol inomphumela wokuvimbela ku-inhibitory kumaseli womdlavuza we-ovarian wabantu.
4. Isicelo
1. Kusetshenziswa ekwelapheni i-leukemia, umdlavuza we-pancreatic, umdlavuza webele, umdlavuza webele, umdlavuza wendlala yesinye, i-melanoma, umdlavuza wesibindi namanye ama-tumors.
2. Ingasetshenziswa ekuvinjelweni kwesifo se-anti-host anti-host ngemuva kokufakelwa kwethambo
3. I-Lupeol iyi-triterpenoroid esebenzayo ekhemisi. Inezakhiwo eziningi zokwelapha ezingaba khona.
I-4. I-Lupeol iyi-triterpenoid, ene-antioxidant eqinile, i-antimutagenic, anti-inflammatory, kanye nezimpawu ze-antiarthric, futhi zingasetshenziswa ezinhlelweni zemithi.
5.1COMA:
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Items
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Standards
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Results
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Purity（HPLC）
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Lupeol≥98%
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98.6%
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Appearance
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White powder
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Conforms
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Physical characteristics
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Particle-size
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NLT100% 80目
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Conforms
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Loss on drying
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≤2.0%
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1.54%
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Heavy metal
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Total metals
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≤10.0ppm
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Conforms
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Lead
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≤2.0ppm
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Conforms
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Mercury
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≤1.0ppm
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Conforms
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Cadmium
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≤0.5ppm
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Conforms
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Microorganism
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Total number of bacteria
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≤1000cfu/g
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Conforms
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Yeast
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≤100cfu/g
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Conforms
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Escherichia coli
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Not included
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Salmonella
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Not included
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Not detected
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Staphylococcus
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Not included
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Not detected
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Conclusions
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Qualified
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QC: UGuo Shan Qa: feng li
Izigaba zomkhiqizo : Imikhiqizo eshisayo eshisayo
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