Funda ekusetshenzisweni kwe-Oligo-Xylulose ekuthuthukiseni i-Irritable Bowel Syndrome
I-Irritable Bowel Syndrome (IBS) ibhekisela eqenjini lama-Syndromes emitholampilo kufaka phakathi ubuhlungu besisu, ukubhekana nokuphazamiseka kwamathumbu kanye nokunye okubonakalayo, okuphikelelayo noma okuphindaphindwayo, ngemuva kokuhlolwa, ngemuva kokuhlolwa kwezimpawu ezingezona . Lesi sifo singenye yezifo ezisebenza kakhulu zamathumbu. Ezinhlokweni zemibuzo zabantu abajwayelekile, lezo ezinezimpawu ze-IBS kubikwa ukuthi zingama-10% -20% eYurophu nase-United States, neqembu eBeijing, China, kubikwe u-8.7%. Iningi leziguli lincane futhi lineminyaka ephakathi nendawo, kanye nokuqala kwesifo ngemuva kweminyaka engama-50 ubudala akuvamile.
I-Irray Bowel Syndrome (IBS) igcizelelwa kabanzi ngenxa yokwanda kwayo okuphezulu kanye nokwelashwa okunzima ngokwengeziwe, futhi i-etiology yayo ne-pathogenesis ayikacaciswa futhi kungahle kuhlobane nezinto ezahlukahlukene. Njengamanje kukholakala ukuthi isisekelo se-pathophysic se-IBS ikakhulukazi ama-Dynamics ase-gastroidwenal kanye nemizwa ye-visceral engajwayelekile, kuyilapho izindlela ezibhekele lolu shintsho zingacaciswanga.
Azikho izidalwa ezibalekayo eziye zakhiwe ezindlekweni zanoma yisiphi isiguli ngalesi sifo, ngakho-ke kungacatshangwa ukuthi izimpawu azibangelwa umzimba othile wokuqamba. Ezifundweni zesayensi ye-IBS, ukwehla kwenani lama-anaerobes aphelele, ama-bifidoobacteria, kanti inani le-canogenic elingaba khona i-borveridium ehlukile, elenza ingxenye encane ye-flora yamathumbu, iye yanda.
Amalungiselelo ama-micrococilogical, owaziwa nangokuthi abalawuli be-microocological noma amalungiselelo endalo, asuselwa kwimigomo ye-microcology, ukulungiselela ama-microocological ageters, nokusebenzisa imali ejwayelekile enobunzima futhi engenangozi kumgcini impilo yomgcini (izilwane, izitshalo kanye nabantu) noma ukufeza isimo esifanelekile sempilo. Amalungiselelo ama-micrococilogical ahlukaniswa abe yi-probitootic, i-prebiotic kanye nama-synbiotics.
I-OligosacCharide, eyaziwa nangokuthi i-xylo-oligosaccharide (i-xylo-oligosaccharide), i-oligosaccharide esebenzayo ehlanganisa ama-molecule we-xylose ahlanganiswe ndawonye yi-beta (1-4) amabhondi e-glycosic futhi yi-plycosidic bond futhi i-plycosidic bond futhi iyinto ebonakalayo yemvelo. I-Prebiotic yimizamo yokuthola impilo ethuthukisiwe eshukumisela ukukhula kanye / noma umsebenzi wegciwane elilodwa noma ama-bacterium ambalwa asevele ehlala ekoloni, inzuzo esebenza ngezakhi zokudla umgcini. Empeleni i-Prebiotic iyindlela ethile yokudla kwekholoni. Njenge-prebiotic, kumele ibe nezimo ezi-4 ezilandelayo:
● Yiba sengxenyeni engenhla yepheshana lesisu, ie hhayi i-hydrolyzed futhi ungangeniswa ngumgcini. ● Ukwazi ukukhetha ngokukhetha ama-bacterium athile azuzisayo (ama-bifidoobacteria, njll.) Ephepheni lamathumbu ukukhuthaza ukukhula nokuzala kabusha noma kusebenze imisebenzi ye-metabolic. ● Ingakhuphula ukwakheka kwama-flora avelele epheshana lamathumbu elizuzisa impilo. ● Ingadlala indima ekuthuthukiseni impilo yomgcini. I-OligosacCharide ingakwazi ukutholakala kakhulu i-bifidoobacteriacteriacteriacteriacteriacteria, lungisa i-bactera yamathumbu, ukwenqaba ama-bacterium ama-pathogenic, uphathe uhudo, futhi uvikele umsebenzi wesibindi. Njengamanje, ukwanda kwe-bifidoobacteriacteriac emzimbeni womuntu ikakhulukazi ngokuphathwa ngomlomo kwamalungiselelo obukhoma amagciwane futhi kushukumisela ukwanda kwayo kwemvelo epheshana lesisu. Ngokucabanga ngokuqhathanisa, usebenzisa ama-probiotic ukwenza i-bifidoobacterium ngokwemvelo epheshana lamathumbu liphephile kakhulu, lizinzile futhi lisebenza ngokwengeziwe kunokuthatha amalungiselelo obukhoma abukhoma ngomlomo.
Ucwaningo luye lwabonisa ukuthi i-Xylo-Oligosaccharide inesilinganiso sokusiza esingu-90% sokuqunjelwa, ama-81.1% okuqhakaza, ama-57% okudla okuyisisu, ikakhulukazi isifo sohudo esilinganiselwe, ukuqunjelwa kanye nokuqhakaza. I-OligosacCharide ekwenzeni ngcono amathumbu okucasulayo eziphethweni ezinhle, u-Oligo-Xylulose ku-acid, ukuqina kokushisa kulungile (kwimvelo ye-acidic pH 2.3-8.0, ukufudumeza kuya ku-100 ℃ nakho akubolile (Inani lokudla lincane (nsuku zonke Ukudla umthamo osebenzayo we-0.7-1.4 g), unganconywa njengokwelashwa okuzuzisayo kwe-Irritable Bowel Syndrome yamalungiselelo amancane emvelo.
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